ELISA Substrates and Reagents
American Research Products Inc BoVine Heat shock protein HSP
BoVine Heat shock protein HSP 90-alpha (HSP90AA1) ELISA kit from CUSABIO Detection Range 6 25 ng/mL-400 ng/mL Sensitivity 1 56 ng/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Medchemexpress LLC Spondin-2/SPON2 Protein, Human (HEK293, His) | ≥ 95% | Approximately 38-47 kDa | 250 UG
Spondin-2/SPON2 Protein, Human (HEK293, His) | ≥ 95% | Approximately 38-47 kDa | 250 UG
ABclonal Technology p-AMPKa1-T183-AMPKa2-T172
The protein encoded by this gene belongs to the ser thr protein kinase family It is the catalytic subunit of the 5 -prime-AMP-activated protein kinase (AMPK) AMPK is a cellular energy sensor conserved in all eukaryotic cells The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways Alternatively spliced transcript variants encoding distinct isoforms have been observed
ABclonal Technology Phospho-NF-B2-S866/S870
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB) The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner The p100 full-length protein is co-translationally processed into a p52 active form Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas some of which may result in the formation of fusion proteins There is a pseudogene for this gene on chromosome 18 Alternative splicing results in multiple transcript variants
ABclonal Technology Phospho-PPP1CA-T320 Rabbit pAb
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Genscript Corporation CEACAM-8/CD66bBiotin His
Eosinophils and their products are likely important in the pathophysiology of allergic diseases such as bronchial asthma and in host immunity to parasitic organisms CD66b (CEACAM8 CGM6 NCA-95) is a single chain GPI-anchored highly glycosylated protein belonging to the carcinoembryonic Ag supergene family CD66b is an activation marker for human granulocytes
Meso Scale Discovery R-PLEX Rat Osteopontin ASYQP
The Meso Scale Discovery R-PLEX Rat Osteopontin Assay measures osteopontin in rat serum plasma and cell culture supernatants using electrochemiluminescence for high sensitivity It requires 50 L or less of sample and is compatible with Meso Scale Discovery instruments like the QuickPlex SQ 120 The assay s detection range is 45 to 50 000 pg/mL It includes a plate with capture antibodies detection antibodies with electrochemiluminescent labels and a calibrator with recombinant rat osteopontin
ABclonal Technology Phospho-AKT1-S473 Rabbit pAb
This gene encodes a member of the AKT serine-threonine kinase family (AKT1), which is involved in cell signaling. AKT proteins contain a pleckstrin homology domain, kinase domain, and a regulatory domain. They are phosphorylated by PI3K and play a key role in regulating cell proliferation, survival, metabolism, and angiogenesis. Activated by phosphatidylinositol 3,4,5-trisphosphate (PIP3), AKT proteins regulate numerous cellular functions and are critical for tumor cell survival, inhibiting apoptosis and regulating the mTOR pathway. AKT1 mutations are associated with cancer types, including breast, colorectal, and ovarian cancers, as well as disorders like Proteus syndrome and Cowden syndrome. Multiple spliced variants of this gene exist.